Semax

Semax Synthetic ACTH(4-7) Analogue | Research Use Only

Semax is a synthetic heptapeptide analogue derived from the adrenocorticotropic hormone (ACTH) fragment 4-7, with the addition of a Pro-Gly-Pro C-terminal tripeptide sequence that confers enhanced metabolic stability and prolonged biological activity relative to the native ACTH fragment. Originally developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, Semax has been extensively investigated in preclinical research examining central nervous system function and neuroprotective mechanisms.

In laboratory and animal model studies, Semax has been investigated for its effects on Brain-Derived Neurotrophic Factor (BDNF) expression and neurotrophin signaling pathways. Research applications include neuroprotection studies in ischemic and hypoxic injury models, cognitive function and memory research, and investigations of dopaminergic and serotonergic system modulation. Additional research areas include anxiety and stress response models, attention and learning pathway studies, and preclinical investigations of neurological recovery mechanisms. Semax is widely utilized as a research tool in studies examining neurotrophic factor regulation and central nervous system plasticity.

Research Specifications:

• Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: 813.93 g/mol
• CAS Number: 80714-61-0
• Purity: ≥98% (HPLC verified)
• Form: Lyophilized powder
• Storage: -20°C, protected from light and moisture

For Research Use Only. This product is not intended for human or veterinary use, diagnosis, or treatment. Not evaluated by the FDA. For qualified research applications only.