Cagrilintide

Cagrilintide Long-Acting Amylin Analogue | Research Use Only

Cagrilintide is a synthetic, long-acting analogue of human amylin (islet amyloid polypeptide / IAPP), structurally modified with a fatty acid conjugation via linker to extend plasma half-life beyond that of native amylin. It functions as an agonist at amylin receptors — heteromeric complexes of the calcitonin receptor paired with receptor activity-modifying proteins (RAMP1, RAMP2, RAMP3).

In preclinical and investigational research, cagrilintide has been studied in models examining amylin receptor signaling pathways, energy homeostasis, gastric motility, and metabolic regulation. It has been utilized in combination studies alongside GLP-1 receptor agonists to investigate complementary receptor mechanisms in metabolic research models.

Research Specifications:

• Type: Fatty acid-conjugated synthetic amylin analogue (37 amino acid backbone)
• Target: Amylin receptors (AMY1/AMY2/AMY3)
• Purity: ≥98% (HPLC verified)
• Form: Lyophilized powder
• Storage: -20°C, protected from light and moisture
• Molecular Weight: Verify against supplied COA

For Research Use Only. This product is not intended for human or veterinary use, diagnosis, or treatment. Not evaluated by the FDA. For qualified research applications only.