MOTs-C

MOTS-c: Mitochondrial Derived Peptide Research Use Only | ≥99% Purity

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a naturally occurring mitochondrial-derived peptide encoded within the 12S ribosomal RNA gene of the mitochondrial genome. As a member of the emerging class of mitochondrial-derived peptides (MDPs), MOTS-c has attracted significant research interest for its role in mitochondrial-nuclear communication, metabolic homeostasis signaling, and cellular stress response pathways in controlled laboratory settings.

MOTS-c has been studied in preclinical research models for its interactions with AMPK (AMP-activated protein kinase) signaling pathways, glucose metabolism regulation, and insulin sensitivity mechanisms, making it a research tool of particular interest to investigators studying mitochondrial biology, metabolic signaling, and cellular energetics.

All USA Made Peps MOTS-c is tested by an independent laboratory on every shipped lot (chromatographic purity by UPLC with area normalization, and identity by mass spectrometry); every lot we have published has tested at 99% or higher, our written guarantee is 98.0% (see the specification block), and each shipped lot is supplied with a full Certificate of Analysis.

Available size:

• MOTs-C – 10mg per vial (10 vial pack)
• MOTs-C – single vial, 10 MG

Supplied as lyophilized powder. Store at -20°C. For research use only.

For the identity data, the sequence, and what a MOTs-C certificate should show, see our guide: What Is MOTS-C?

For Research Use Only. Not for human or animal use. Not FDA-approved. Not intended to diagnose, treat, cure, or prevent any disease or condition. For in vitro laboratory research purposes only. Buyer assumes full responsibility for lawful use in their jurisdiction.

Chemical identity & references
PubChem CID 146675088 · UniProt A0A0C5B5G6 · CAS 1627580-64-6 · C101H152N28O22S2, 2174.6 g/mol

Molecular weights shown are nominal identity values; salt or complex form and net peptide content are stated on each lot’s Certificate of Analysis. Verify this lot’s COA.